Scilla
maritima, Urginea maritima (Squill)
Family:
Liliaceae
Part
Used: Bulb (inner scales)
Active Constituents:
Cardioactive glycosides (proscillaridin,
scillaren A, at least 25 others), mucilage
Medicinal Actions:
Cardio-tonic,
diuretic, expectorant, mucolytic
Medicinal Uses:
1.strong
diuretic
2.increase
mucous secretion clear lungs in 20 to 40 hours good for pneumonia
3.cystic
fibrosis but in a lower dose
4.
5.Felter
states that the specific indications for use of Scilla include chronic cough
with scanty, tenacious mucus, little expectoration; dropsy dependent upon a
general asthenic condition and without fever; scanty and high colored urine
with a sense of pressure in the bladder; renal over-activity with inability to
retain the urine.
6.The
cardiac glycosides create positive inotropic and negative chronotropic effects
on the heart due to the cardiac glycosides.
The physiological effects of the glycosides are strong. The absorption of the glycosides is high
(15% for scillaren and 20-30% for proscillaridin) and they have a long
half-life of up to 24 hours. It is
indicated for use in mild to moderate heart failure. It can increase arterial pressure more strongly than digitalis
does. It is a strong diuretic and edema
responds strongly to Scilla.
Scilla is also used as an
expectorant for the lungs. It is a
strong mucolytic and expectorant. In
higher doses it can increase bronchial secretions while in small doses, it decreases
secretions. This combination of actions indicated Scilla for use in right-sided
heart failure to reduce or prevent pulmonary edema and dependent edema.
Toxicity:
The fresh bulb will cause blistering
of the skin if handled excessively.
Overdose can lead to nausea, vomiting, purging, GI inflammation, and
decreased volume of bloody urine, dullness, stupor, intermittent paralysis and
convulsions and may lead to death in 10-24 hours.
Pharmacy:
Tincture (1:5): 5 drops to 20 drops TID or 0.5 ml – 2.0 ml
TID
SE Powder (0.2% proscillaridin) -
0.1 – 0.5 gm